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Themed collection Coronavirus articles - free to access collection

156 items - Showing page 1 of 3
Editorial

Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research

Rank: 3
Best Companies rank: 7

Graphical abstract: Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
From the themed collection: 广西4批次水泥产品质量不合格
Editorial

Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?

“中国银行业面临的逆风将延续很长时间,”他说。“除了盈利来源减少,它们还将不得不为坏账带来的亏损做好准备。”
As a brand, Acura sold 167,843 cars and trucks last year, a 1.5% increase. Lexus, Toyota’s premium brand, was up 13.7%; BMW was up 9.8%, Audi was up 15.2% and Mercedes-Benz was up 6.5% in a U.S. market that was very favorable for luxury vehicle manufacturers.

Graphical abstract: Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
Open Access Accepted Manuscript - Highlight

Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities

Open Access Perspective

Soft matter science and the COVID-19 pandemic

As fall arrived and school began, D'Aloisio felt immense pressure to deliver for his backers. He needed to whip his algorithm into better shape, so he contracted a team of Israeli coders who specialize in natural language processing. Searching on Google, he found and hired a retired professor living in Thailand who'd written seminal books on the topic. 'He became our main scientist,' says D'Aloisio. 'He now works at Yahoo! in the Sunnyvale office.'

Graphical abstract: Soft matter science and the COVID-19 pandemic
Open Access Perspective

Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective

在主要的美国航空公司中,全美航空公司拥有最高的假日航班准点率,在榜单上排名第五,去年感恩节和圣诞节期间的航班延误率为15.57%。与此同时,计划和全美航空公司合并的美国航空公司(American Airlines)排名倒数第四,FlightAware网站的数据显示,该公司航班延误率达到19.7%。

Graphical abstract: Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
From the themed collection: 中介私自将租赁变为贷款属欺诈
Perspective

Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic

凡是这家汽车服务公司的忠实员工在效力满10年后,都可获得一份奖励:在佛罗里达州波卡拉顿的一处度假胜地欢度周末(此地距该公司总部仅15分钟车程)。这项福利此后每5年都可以享受一次。
担忧和愤怒要深刻得多,也更不吸引人。
"I'm always amazed at how many people tell their co-workers about their job search," Kay says. "That's one of the worst things you can do." Ideally, you wouldn't tell any co-workers, but you may have to if you want them to serve as references. In that case, Kay says, "you need to pick people who you really trust, who don't have a hidden agenda and who won't let it slip."
This umbrella protects your dogs from the sun and rain.

Graphical abstract: Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
From the themed collection: 宜家将于月底前实现全面LED化
Perspective

Trends and targets in antiviral phototherapy

Funded partly by firms and companies, the charity places top graduates in schools serving low-income communities for at least two years, knowing full well that many of them will leave the profession at the end of this period.
中国依然是美国政府债券的最大持有人,10月份中国也减持到1.25万亿美元。
一个更大的侧影
在岛上海边的总督大楼,数万名支持群众等待罗塞略在宣誓就职典礼后的到来,手握着伞挡住炽热阳光。

Graphical abstract: Trends and targets in antiviral phototherapy
Minireview

A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays

当支持者在周一早些时候涌向总督大楼,一人高喊,"今天,新的波多黎各开始了!" 随着其他人的欢呼,包括那些拿着美国国旗的群众。

Graphical abstract: A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
From the themed collection: 大批产学研合作项目落户湾区
Minireview

Novel biosensing methodologies for ultrasensitive detection of viruses

The Datafolha poll was based on interviews with 693 fans at the Mineirao stadium in Belo Horizonte and had a statistical margin of error of 4 percentage points.

Graphical abstract: Novel biosensing methodologies for ultrasensitive detection of viruses
Application

Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug

v. 施压
《何以笙箫默》

Graphical abstract: Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
Open Access Review Article

ACE2 as a potential therapeutic target for pandemic COVID-19

据当地媒体报道,这一犯罪团伙设在广西壮族自治区首府南宁,他们向腐肉中注射化学药品,使其增重50%,这样每吨腐肉便可获利16000元人民币(合1750英镑)。
Amid rising pollution and a strengthening yuan, the capital city saw its tourist numbers drop to 4.20 million visits from January to November from 5.01 million visits in 2012, according to China Daily, citing a report from China Tourism Academy and Beijing Commission of Tourism Development. An earlier report based on a survey of domestic travel agents showed that visitors to the capital declined by roughly 50% in the first three-quarters of the year compared with a year earlier.

Graphical abstract: ACE2 as a potential therapeutic target for pandemic COVID-19
Open Access Review Article

Diagnostic technologies for COVID-19: a review

Best Companies rank: 12
5. 2012年搞笑诺贝尔奖之化学奖

Graphical abstract: Diagnostic technologies for COVID-19: a review
Open Access Review Article

Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review

At Japan Expo, we are very honored to interview Gen Urobuchi and also begraced with the presence of Nitro+ president Takaki Kosaka.Let's begin.Translated by Emmanuel Bochew.
2017年我国继续同步提高企业和机关事业单位退休人员的基本养老金水平,惠及1亿多人。
Company: Binary Group
vt. 祝贺

Graphical abstract: Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
Open Access Review Article

An overview of key potential therapeutic strategies for combat in the COVID-19 battle

I may say "I'm terminating you because you didn't meet performance measures." I'm not going to say it's because you're a pain in the butt and piss people off every time you interact with them.

Graphical abstract: An overview of key potential therapeutic strategies for combat in the COVID-19 battle
Open Access Review Article

Potential repurposed SARS-CoV-2 (COVID-19) infection drugs

Only two people know the Oscars winners list and supervise the counting procedures - PwC tax adviser Martha Ruiz and Brian Cullinan an accountant.
年龄:46

Graphical abstract: Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
Open Access Review Article

Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale

面对批评,梅耶尔4月份接受本刊采访时为自己的决定进行了辩解,她说人们“错误地把这项措施视为行业条例。”她表示,自己需要员工在办公室工作,目的是鼓励他们进行合作与创新。目前看来,这个不同寻常的做法可能正在对雅虎产生积极影响——2012年梅耶尔上任以来,这家公司的股价已经上涨了一倍多。

Graphical abstract: Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
Review Article

In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections

"For IBM, although they regularly top the list of U.S. patentees by volume of patents each year, the Top 100 Global Innovators listing evaluates not just volume, but also success, globalization and impact," said Bob Stembridge, analyst with Thomson Reuters.

Graphical abstract: In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
From the themed collection: 环保家居建材消费旺盛
Review Article

Antiviral drug discovery: broad-spectrum drugs from nature

overall
Further, 32 out of the 50 new selected female billionaires started their businesses from scratch.
Confidence and a good elevator speech can take any pitch to the next level. The first marketing any company experiences comes from its founder. Spend time learning how to share your vision without coming across as “salesy.” Don’t be afraid to ask for the sale, but remember: the client is always the focus.
当很多千禧一代很难找到工作或在低技能岗位上将就时,凭着项目本身与公司合作伙伴的联系以及校友网络,这些管理学硕士项目的毕业生获得了很高的就业率。

Graphical abstract: Antiviral drug discovery: broad-spectrum drugs from nature
Review Article

Influenza neuraminidase: A druggable target for natural products

Getting sector calls right was the least of any investor’s problems this year because, outside of the brilliance of U.S. stock gains, the lights were off around the world.
Song “Chang’er”(Li Yugang and three Chinese astronauts)
The new governor also seeks to privatize services such as the generation of energy, establish an office to oversee and distribute federal funds to cut down on corruption, and to create financial incentives for doctors to boost the number of dwindling specialists.
['tnl]
2. The Hammocraft

Graphical abstract: Influenza neuraminidase: A druggable target for natural products
Critical Review

Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle

马特达蒙凭借他在《火星救援》中扮演的被困宇航员一角而荣获喜剧类最佳男主角奖项。
"Well, I am going to have a Cabinet that looks like America," the former secretary of state replied. "And 50 percent of America is women, right?"

Graphical abstract: Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
Critical Review

The role of biosensors in the detection of emerging infectious diseases

Foss 还指出别人的推荐信有时间标记。如果你一周之内有五个新的赞那样看起来会很可疑,这些赞不像是真心的,好像你在刷好评,让别人说你好。

Graphical abstract: The role of biosensors in the detection of emerging infectious diseases
Communication

Quantitative determination of mechanical stability in the novel coronavirus spike protein

人们对于可穿戴设备销量的估计各不相同。研究公司IDC认为,这类设备今年的销量将超过1,900万件量,达到去年的三倍以上。到2018年,它的销量将会达到1.119亿件。瑞士信贷(Credit Suisse)预计,在接下来的2-4年中,这个行业的价值将会高达300亿至500亿美元。不过,在这一切实现之前,这个方兴未艾的市场需要摆脱人们对于“穿戴这种设备就是出丑”的成见。

Graphical abstract: Quantitative determination of mechanical stability in the novel coronavirus spike protein
From the themed collection: 个人车位共享“叫好不叫座”
Communication

Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations

The appointment was announced by Steven Ciobo, the Australian minister for trade, tourism and investment, on Feb 21. The Chairman of the China National Tourism Administration, Li Jinzao, was present.
网络红人前10名的微博粉丝数加起来超过了4000万。其中最著名的Papi酱签署的视频广告价值竟然达到了令人震惊的2200万元。
Belgium, for example, has less than a tenth of the population of Russia, its rival in the group stage, but is regarded as a far greater threat. And then there is Uruguay, which despite fewer than 4 million citizens -- barely a sixth of the population of greater S?o Paulo -- is one of the teams Brazil would least like to meet on its way to the final. How is this so?
Special machines pump helium gas into the bubble solution.

Graphical abstract: Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
Communication

MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling

Index: 97.8
节目9 相声《这事儿不赖我》,曹云金 刘云天
祝你在新的一年里身体健康,多福多寿。
Last year was the hottest on earth since record-keeping began in 1880, scientists reported on Friday, underscoring warnings about the risks of runaway greenhouse gas emissions and undermining claims by climate change contrarians that global warming had somehow stopped.

Graphical abstract: MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
Communication

Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses

spontaneous
恭贺新年。

Graphical abstract: Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
Communication

Inhibition of SARS coronavirus helicase by bismuth complexes

得益于网络游戏产业的快速增长,网易公司创始人丁磊的财富翻倍至960亿元,超越了百度公司董事长李彦宏,在IT富豪榜上排名第三。
公司:(Wonderbag)Natural Balance公司
She is home-tutored alongside her younger sister Mackenzie, who also stars in the Dance Moms series and with whom Maddie released a fashion line called The Maddie & Mackenzie Collection last year.
现金全款购房者。难以取悦的贷款人。暴涨的价格。匮乏的挂牌信息。这些现实,都困扰着购房者,使找房子的过程让人倍受打击。不幸的是,在新的一年,购房者们可能依旧需要在卖方市场里打拼。
节目25 歌曲《风吹麦浪》,李健 孙俪

Graphical abstract: Inhibition of SARS coronavirus helicase by bismuth complexes
Open Access Edge Article

Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning

如果你热爱生存,那么脑死亡是一件不美好的事。而且,如果你想用空闲的大脑来替换,那你是绝对找不到的。当然,也许有一天,我们能将大脑放入头骨中,但是大脑跟别的器官不同。它装有你所有的思想和记忆。人们能在你头里放一个新的大脑,但是你还是不存在,所以人造大脑这种想法看起来很荒谬。
"How many patients do Chinese doctors see a day? It can be more than 50," he told China Daily. "How can we have the time and energy to do research or publish papers?"
Strachan says that he believes that the IP-BOX uses the same method employed by the FBI to unlock the iPhone 5c used by Syed Farook, without Apple's help. The FBI is now offering to help other law enforcement agencies seeking to unlock an iPhone, iPad or Apple iPod touch. Apple is trying to discover how the FBI unlocked the phone so that it can issue a software update to close the vulnerability.

Graphical abstract: Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
Open Access Edge Article

A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers

During the 40 days of Chunyun period, the inter-city transportation faces great challenges. The demand for tickets far exceeds the supply. Various measures are adopted to alleviate the problem by opening many temporary trains (numbers starting with letter L), extending the working hours of booking office and opening up more booths.
However, this year it is ranked in eighth place.

Graphical abstract: A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
From the themed collection: 四月涂料市场动态大盘点
Open Access Edge Article

Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods

The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.

Graphical abstract: Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
Open Access Edge Article

Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors

By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.

Graphical abstract: Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
Open Access Edge Article

Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir

葡萄牙完全使用可再生能源供电四天
[.k?ntri'bju:n]
谁都记得几个月前,哈里王子因为媒体对其女友梅格汉·马克尔的猜测而发表了出人意料的公报。

Graphical abstract: Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
From the themed collection: 宜华木业拟更名宜华生活科技
Open Access Edge Article

Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes

但当格雷泽给我们带来《皮囊之下》,这部经过他长期酝酿的,由荷兰作家米歇尔·法柏的科幻小说改编的电影时,真是让人惊叹:欢快,不安,大胆。斯嘉丽扮演的外星人藏于人类的皮囊里,穿梭在格拉斯哥街道和商场,不亚于一位一线明星。现实生活中的路人在镜头中完美的展现,而隐身的约翰森面无表情的估算着三个地球人可被利用的热量值。接着演员带着被色诱的人类离开人群,来到她自己的地方:一个神秘的黑暗的洞穴中。在这里,情色恍惚间,人类贡献自己的肉体,被囚禁,被养殖成为食物,谁知道呢,又或许是人类的灵魂。
The 2014 ranking of 100 programmes for working senior executives is headed by Trium, runby HEC Paris, the London School of Economics and Stern School of Business at New York University. The top five places continue to be dominated by intercontinental EMBAs.
这是第一首真正意义上的007系列电影主题曲(再说一次,詹姆斯·邦德前两部电影开场只使用了管弦乐),至今仍然是最好的一首。雪莉·巴赛得到了唱出自己心声的机会,她很乐意接下这个挑战。这首歌增添了《金手指》中反派人物奥里克的危险性(还有吸引力),但这仅仅只是雪莉·巴赛歌曲魔力的一部分。詹姆斯·邦德傲慢自大、英雄主义、诱惑人心、虚幻迷离,但谁在乎啊?这首歌就是为詹姆斯·邦德所作,歌词充满男子气概,歌手的演唱简直完美。

Graphical abstract: Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
Accepted Manuscript - Paper

A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring

Open Access Paper

Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)

['tmpj?n]

Graphical abstract: Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
Paper

A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood

学员平均年龄:37岁

Graphical abstract: A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
Open Access Paper

Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations

After weeks of rumors, Phil Jackson failed to move Carmelo Anthony and Derrick Rose, two players who absolutely should have been traded for the long-term benefit of the franchise.
n. 休息寓所,撤退,隐居

Graphical abstract: Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
Open Access Paper

The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives

8、《自杀小队》
乔斯的母亲因玛·克萨达在接受《西班牙日报》采访时表示,她的儿子想要给自己的乐队“Los Salerosos”(大意为“冒失鬼”)购买乐器。他在乐队里担任小号手。
However, before starting their EMBAs, there is already a wide gap in salaries, with women earning on average 15 per cent less than men, at $111,000 and $128,000 respectively.
达成一个全球性气候协议的下一次大尝试,将是在来自世界各地的谈判代表今年12月聚集巴黎的时候。气候变化问题的政治活动人士上周五不失时机地引用2014年的温度记录为证,表明采取强有力行动的必要性。

Graphical abstract: The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
From the themed collection: 连天红事件何时休?
Open Access Paper

Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease

出手阔绰的美国公司正迫使英国同行提高从新入行者到顶级风云人物的薪资——尽管这并未阻止富尔德(Freshfields)的私募股权明星戴维希金斯(David Higgins)在圣诞节前夕跳槽到凯易律师事务所(Kirkland & Ellis)。精品专业律所通过提供更快、更专注的服务来吸引客户。
Captain America: Civil War will hit theatres May 6, 2016. Who's side are you on?

Graphical abstract: Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
Open Access Paper

Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro

2.The Fresh Prince of Bel Air was Almost Bankrupt
The Sports Illustrated Swimsuit Issue model Kate Upton stands 8th on the world's most beautiful women of 2015 list. This modern fashion model was at No. 2 in last year list. She also was named the sexiest women by People magazine.

Graphical abstract: Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
Open Access Paper

Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein

在接受《每日电讯报》采访时,玛蒂说:“我再也无法过上平凡人的生活了。因为大家很容易认出我来,甚至当我出去玩或是和朋友吃冰淇淋都能被路人认出来。”

Graphical abstract: Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
Paper

Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide

The circular also stressed zero tolerance for cheating.
My Sunshine
As a measure of that fall, 10 works have sold at auction for more than $100 million since 2004, and all of them were made by modern or contemporary artists in the past 120 years. Older paintings have seen their value, in relative terms, level off or decline. The trend was plain to see in recent weeks, as London’s auction houses tried to find buyers for their latest tranche of old masters. As has been the case in recent years, there were few works by major names.
One highlight of last year's box office was seven high-quality domestic films listed on the top 10 earners, including 'Monster Hunt', a live-action hybrid, and 'Monkey King: Hero is Back', a 3D animation based on the classic ancient story.

Graphical abstract: Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
Open Access Paper

Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses

When did winter become the season of television’s most distinguished content? The fall season, with its organized and heavily publicized broadcast-network premieres, still gets the attention, but a greater number of interesting shows now arrive on cable, broadcast and online in the first quarter of the year.
Meanwhile producer prices fell 4.9 per cent year-on-year in February, as expected, compared to a 5.3 per cent fall in January. The drop was the smallest in eight months.

Graphical abstract: Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
Open Access Paper

The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor

下面就是今年汽车业所经历的高峰和低谷:
这种旅行枕可以随意弯曲变形,您的头怎么放都行。
Mavericks owner Mark Cuban has made riskier bets than this, though, and he didn't part with much of consequence (Justin Anderson and a fake first-round pick) for a shot at working Noel into a lob-finishing/rim-protecting life as the next Tyson Chandler.

Graphical abstract: The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
From the themed collection: 智能家居或成BAT下一个竞逐点
Open Access Paper

Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study

3. You support the teams that I support.
On the sales front, General Motors and Ford F -0.13% lost market share to Chrysler, which leveraged its Jeep brand to previously unimagined heights – and then, metaphorically left its heritage behind when it established legal domicile in the Netherlands and changed its name to FCA US LLC.
New Chinese firms on the list include Vanke, China Railway Engineering Corporation (CREC) and China Taiping Insurance.

Graphical abstract: Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
Open Access Paper

Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework

BrandZ表示,最具价值品牌的表现超过金融市场,这说明了它们的财务实力和对股东的价值。
支持:美国国家评论协会将最佳电影、最佳男主角和最佳女主角奖颁给了这部电影。

Graphical abstract: Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
Open Access Paper

Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach

Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.

Graphical abstract: Several coumarin derivatives and their Pd(ii) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
Open Access Paper

Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors

Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.

Graphical abstract: Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
Open Access Paper

Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins

Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.

Graphical abstract: Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
Open Access Paper

Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform

The improvements in education levels mirrored the development of China's education system. Independent research into China's education situation showed that overall education development was better than the world average last year, Yuan Guiren, minister of education, said in March.
今年初,麦基在接受媒体采访时说:“虽然似乎有悖于直觉,但尽可能提高长期利润的最佳途径就是不要把利润作为公司的首要目标。”
East New York in Brooklyn will be the test case when the Department of City Planning presents initial recommendations early next year. After that, the rezoning process could begin for the neighborhood, among the city’s poorest. A proposal for west Flushing in Queens is next.

Graphical abstract: Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
Open Access Paper

A modular microarray imaging system for highly specific COVID-19 antibody testing

前述北京微信用户Robin Wang说,11年前他是一位忠实的QQ用户,但现在已经停用这款即时通讯服务,因为它显得不够专业。但自从在手机上下载微信之后,他发现多数同事和朋友都在上面,现在大家都通过语音邮件交流了。
"Moreover, most Chinese families only have one child, so many of us return to China because we want to stay close to our family and friends," said a student surnamed Su, who gave up his job in the UK and returned to take care of his mother in China.

Graphical abstract: A modular microarray imaging system for highly specific COVID-19 antibody testing
Open Access Paper

Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms

美联储政策中任何意外举动的潜在影响,在2013年的“缩减恐慌”(taper tantrum)中表露无遗,当时,仅是美联储可能很快缩减其超宽松货币政策力度的暗示就足以引发一波全球恐慌。
It is already illegal for employers to discriminate on the basis of race, color, sex, nationality, religion, age, or disability. But a majority of states still don't provide protection to LGBT individuals in the workplace. Apple (AAPL, Fortune 500) CEO Tim Cook wants to put an end to this discrepancy. In a November Wall Street Journal op-ed entitled "Workplace Equality Is Good for Business," Cook urged the passing of a federal law to protect workers from discrimination based on sexual orientation.
上周,卢彦被任命为北京市推进京津冀协同发展领导小组办公室主任,该举措是为了加速京津冀一体化的协调工作。

Graphical abstract: Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
Open Access Paper

Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening

面试官走进了壁橱,而不是会议室。

Graphical abstract: Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
Open Access Paper

Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations

A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.

Graphical abstract: Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
Open Access Paper

Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets

恭贺新禧,万事如意。
新年的祝福,平日的希冀,愿你心境祥和、充满爱意,愿你的世界全是美满,

Graphical abstract: Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
Open Access Paper

A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation

The report ranks brands based on financial performance, its influence on customers, and its power to command a premium price or drive company sales.
根据这份新报告,在过去20年里,印度是发起反倾销案最多的国家,在1995年至2015年间发起的4990件反倾销案中,印度发起了767件,占比为15%。同期,美国发起了570件,欧盟发起了480件。

Graphical abstract: A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
Open Access Paper

An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19

3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.

Graphical abstract: An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
Open Access Paper

Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies

2017已经是詹姆斯在联盟中的第十四个赛季,但他的场均助攻和篮板竟然还创下了职业新高。在这个赛季的前两个月里,他拿出了整个职业生涯最好的三分表现,但鉴于这已经被各方专家们讨论和剖析,并且被媒体广泛的报道了,我在这里就不加赘述了。
Goldie Blox is a toy company on a mission to redefine the “pink aisle” in toy stores. Men dramatically outnumber women in science, technology, engineering and math (STEM) education and careers, with girls largely losing interest in these topics by age 8. Goldie Blox toys are designed to inspire future engineers by engaging girls in a way that draws on their strong verbal and storytelling skills — while still offering opportunities to build the skills that can later translate into an interest in engineering. And speaking of opportunity, how does a start-up toy company stand out against the big names that have been dominating the toy space since the beginning of time? In a savvy move, Goldie Blox recently released a video that went viral with their take on the Beastie Boys song “Girls.” Though the video was ultimately taken down, Goldie Blox did an excellent job raising awareness of the need to get more women and girls interested in STEM … and of the Goldie Blox toys.

Graphical abstract: Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
Paper

Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material

“尼克是一位优秀的产品思想家,”雅虎移动与新兴产品高级副总裁亚当卡恩(Adam Cahan)说,“他的确代表了他在思索的事物和‘移动’真正内涵的跨世代转变。新一代不仅仅是以移动为先,而且是以移动设备为唯一上网工具。这是一种不同的视角。”
9. 安布罗斯·阿钦摩西尔(Ambrose Akinmusire),《想像中的救世主更容易描绘》(the imagined savior is far easier to paint),Blue Note。小号手安布罗斯·阿钦摩西尔为自己在Blue Note公司发行的第二张专辑注入了类型不固定,富于探索精神的今日之声,有许多歌手和一支弦乐四重奏组合参与。和这张专辑刚发行的时候相比,如今的他有了更多评论社会的迫切与讥讽时局的精神。

Graphical abstract: Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
From the themed collection: 户外LED显示屏的优劣判断
Open Access Paper

A facile assay for rapid detection of COVID-19 antibodies

约60%的学员尚未参加工作,另有30%的学员拥有不到两年的工作经验。

Graphical abstract: A facile assay for rapid detection of COVID-19 antibodies
Open Access Paper

Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses

Dirk Philippa, portfolio manager of Fidelity International’s global property fund, has also cut investments in Hong Kong from a 6-8 per cent overweight two years ago, relative to benchmarks, to a 1 per cent overweight position.
And others simply disappeared:
英国整体排名第三。“强国”排名第四,“文化影响力”排名第五。
When you think of him, your heart would jump between fast and fast.

Graphical abstract: Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
From the themed collection: 专家称:解决租房问题主要靠市场
Open Access Paper

Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2

There were reversals too. Sales of electric vehicles suffered as gas prices leveled off and then fell. Suzuki wound down its presence in the U.S. market, and Volvo looked none too healthy. Sales in China -- now the world's largest auto market -- slowed, and Europe remained deep in a slump, its fundamental overcapacity problems unsolved.

Graphical abstract: Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
Open Access Paper

Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease

然后,他用那把小提琴砸穿了那幅画。
8.身着平底鞋禁止入场,是吗?
难怪现代和当代艺术品拍卖市场的主要玩家佳士得拍卖行把自己的早期绘画大师作品重新宣传为“古典艺术品”。它将于明年4月(原先的计划是明年1月)在洛克菲勒中心(Rockefeller Center)举办早期绘画大师作品及其他历史作品拍卖会,其中包括20世纪作品专题拍卖会。周五(12月18日),佳士得称,它的“古典艺术品”拍卖计划将于明年7月在伦敦公布。

Graphical abstract: Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
Open Access Paper

Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19

Female vocalist: Miranda Lambert
Now, Curry and the Golden State Warriors are right road of adding another accomplishment.

Graphical abstract: Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
Paper

Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties

1. 新闻记者
然而据北京出入境边防检查总站(Beijing General Station of Exit and Entry Frontier Inspection)称,只有14,000名旅客办理了过境免签手续,远低于官方此前预计的20,000人。

Graphical abstract: Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
Open Access Paper

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.

Graphical abstract: Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
Paper

Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract

"Sydney's housing prices shot up because foreign investors are buying trophy assets, in places like Bondi," says Elliot.

Graphical abstract: Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
Open Access Paper

Anti-HIV drug repurposing against SARS-CoV-2

Meanwhile, 78 percent of the civil service jobs offered this year are posts at county or district levels, as the central government seeks to steer more college graduates to jobs at city and county levels, he said.
比利时
胡润研究院称,只有资本净值超过80亿元的女性才有资格入围中国女富豪榜前50名。

Graphical abstract: Anti-HIV drug repurposing against SARS-CoV-2
Paper

Length-scale dependence of protein hydration-shell density

在北大和清华大学之后,中国内地入选该榜单前20名的院校还有中国科学技术大学,该校位居第15位;复旦大学排名第16位,上海交通大学排名第18位,而浙江大学排名第19。
夏普利对这一主题提出了早期的理论,在20世纪50年代和60年代利用博弈论来分析不同的匹配方式。与美国经济学家大卫?盖尔一起,他开发了一个数学公式10个男人和10个女人如何配对才能保证没有人会受益于配对伙伴。虽然这可能有一点影响到结婚和离婚,他们开发的算法已经被用于更好地理解许多不同的市场。
巴蒂表示,中国的大学现如今已经花费百万元巨资聘请国际知名学者,同时还配备了各项最先进的设备。
ICBC’s earnings per share were Rmb0.77, down from Rmb0.78 last year, and a pre-tax dividend per share was Rmb0.2333, down from Rmb0.2554.

Graphical abstract: Length-scale dependence of protein hydration-shell density
From the themed collection: 涨价或开启建材市场新一轮洗牌
Open Access Paper

High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus

后来,通用汽车在1958年设计出一款无人驾驶汽车,其原理是:由线圈感知道路中所嵌入电线的交流电信号,并相应地调整方向盘。然而汽车确实能自主驾驶,但并不能称为第一辆全自动驾驶汽车,因为它必须依赖嵌在地面的电线。在日本的筑波机械工程实验室,津川和他的几个同事发明了世界上第一辆自动驾驶汽车。然而,德国工程师恩斯特·迪克斯被称为无人驾驶汽车的先驱。1987年,他发明的"极速",时速超过90千米(56英里/小时),行驶了大约20千米(12分钟)。7年后,他发明的VaMP,不但可以识别道路标记,而且能定位自己在车道内的位置,还能勘测其他车辆,甚至能判断何时该变道。一年后,他和他的团队发明的自动驾驶汽车,从德国行驶到丹麦,最高时速为180千米(111英里/小时)。整段旅程中,仅有5%左右的路程是人为驾驶。
vi

Graphical abstract: High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
Paper

A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor

The app D'Aloisio designed, Summly, compresses long pieces of text into a few representative sentences. When he released an early iteration, tech observers realized that an app that could deliver brief, accurate summaries would be hugely valuable in a world where we read everything-from news stories to corporate reports-on our phones, on the go. The app attracted the interest of investors around the world, ranging from Hollywood celebrities to Hong Kong billionaire Li Ka-shing, the wealthiest man in Asia.
皮克斯动画公司CEO乔布斯(此时乔布斯已重返苹果公司)在苹果展销会上作演讲,1997年,1月7日
设计师布莱恩-卡朋特和布兰德-霍克因为酷爱户外运动而受到启发,决定想出一种创意方式,能够随处搭吊床。

Graphical abstract: A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
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The pickup in consumption in turn will entice businesses to hire and invest more to keep up with rising sales. The result: The U.S. is likely to grow more than 3% for the first time since 2005.
中国政府鼓励向中小规模的借款人放贷,其中很多贷款者没有信用纪录。分析师预计,在金融上表现活跃但没有信贷渠道的中国消费者有5亿之多。

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